Although it seems that only one or two ocular tissues are dysfunctional in many of the common eye diseases, the causes for those damages could arise from problems of other ocular compartments. Therefore, a study that incorporates as many tissues as possible for comparison between mammalian species is warranted. As a result, disruption of the role in any eye tissue leads to vision problems. Finally, many tissues of the eye enable efficient nutrient supply, removal of waste, and provide structural support necessary for maintaining normal vision. In addition, vision processing occurs in the neural retina (NR), which absorbs the energy in a photon of light, enabling the transformation of energy into electrical force, which then undergoes further secondary order processing before being transmitted to the rest of the brain through the optic nerve.
The anterior segment allows light entry into the eye, controls how much light enters and focuses light to the back of the eye for vision processing. Recently, the development of single-cell RNA sequencing (scRNA-seq) renders transcriptional comparisons feasible.Įach eye tissue plays a crucial role in enabling vision. Differences that may be present at the cellular level remain unknown, and until recently, the tools to compare species with such resolution were limited. However, the form and function of its compartments that make up the human eye are similar across evolutionary time 1. The vertebrate eye has undergone substantial changes since humans diverged from earlier species, including earlier mammals and fish.
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